Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | NCI_IL23-MEDIATED SIGNALING EVENTS |
| Enrichment Score (ES) | -0.64847976 |
| Normalized Enrichment Score (NES) | -1.5662563 |
| Nominal p-value | 0.005791506 |
| FDR q-value | 0.14402252 |
| FWER p-Value | 0.929 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | STAT5A | 2680458 | 695 | 2.835 | 0.0048 | No | ||
| 2 | IL12RB1 | 2230338 5420053 | 927 | 2.406 | 0.0282 | No | ||
| 3 | CXCL1 | 2690537 | 1757 | 1.439 | 0.0050 | No | ||
| 4 | CYLD | 6590079 | 2137 | 1.107 | 0.0011 | No | ||
| 5 | NFKB1 | 5420358 | 2462 | 0.934 | -0.0025 | No | ||
| 6 | UBE2D3 | 3190452 | 3104 | 0.570 | -0.0285 | No | ||
| 7 | ARRB2 | 2060441 | 3420 | 0.442 | -0.0389 | No | ||
| 8 | CHUK | 7050736 | 3694 | 0.353 | -0.0484 | No | ||
| 9 | IL1B | 2640364 | 4058 | 0.263 | -0.0640 | No | ||
| 10 | CCL2 | 4760019 | 4102 | 0.255 | -0.0625 | No | ||
| 11 | IL18 | 6180039 | 4139 | 0.248 | -0.0608 | No | ||
| 12 | JAK2 | 3780528 6100692 6550577 | 4188 | 0.238 | -0.0598 | No | ||
| 13 | ALOX12B | 5340102 | 4522 | 0.188 | -0.0750 | No | ||
| 14 | ITGA3 | 4570427 | 4656 | 0.171 | -0.0796 | No | ||
| 15 | TNF | 6650603 | 4857 | 0.148 | -0.0882 | No | ||
| 16 | BCL3 | 3990440 | 5360 | 0.110 | -0.1136 | No | ||
| 17 | IL12B | 460008 | 7246 | 0.043 | -0.2145 | No | ||
| 18 | PIK3R1 | 4730671 | 7432 | 0.039 | -0.2239 | No | ||
| 19 | XPO1 | 540707 | 7976 | 0.029 | -0.2528 | No | ||
| 20 | IL2 | 1770725 | 8133 | 0.026 | -0.2608 | No | ||
| 21 | IL6 | 380133 | 9755 | 0.001 | -0.3482 | No | ||
| 22 | RAN | 2260446 4590647 | 9782 | 0.000 | -0.3496 | No | ||
| 23 | IFNG | 5670592 | 11703 | -0.032 | -0.4526 | No | ||
| 24 | MALT1 | 4670292 | 11838 | -0.034 | -0.4593 | No | ||
| 25 | ATM | 3610110 4050524 | 11988 | -0.038 | -0.4668 | No | ||
| 26 | IL19 | 6040142 | 12221 | -0.044 | -0.4786 | No | ||
| 27 | SRC | 580132 | 12487 | -0.050 | -0.4922 | No | ||
| 28 | IL18RAP | 3850088 | 12491 | -0.050 | -0.4916 | No | ||
| 29 | IL24 | 1500372 7000167 | 12650 | -0.054 | -0.4993 | No | ||
| 30 | PIK3CA | 6220129 | 12692 | -0.056 | -0.5007 | No | ||
| 31 | IL23R | 3990014 | 12710 | -0.056 | -0.5007 | No | ||
| 32 | IL23A | 6290044 | 12734 | -0.057 | -0.5011 | No | ||
| 33 | FBXW11 | 6450632 | 12804 | -0.059 | -0.5040 | No | ||
| 34 | SYK | 6940133 | 12894 | -0.062 | -0.5078 | No | ||
| 35 | REL | 360707 | 13327 | -0.079 | -0.5299 | No | ||
| 36 | BIRC2 | 2940435 4730020 | 13602 | -0.093 | -0.5433 | No | ||
| 37 | IL17F | 670577 | 13866 | -0.110 | -0.5558 | No | ||
| 38 | PRKCA | 6400551 | 13968 | -0.118 | -0.5595 | No | ||
| 39 | IL17A | 4280369 | 14097 | -0.128 | -0.5645 | No | ||
| 40 | STAT4 | 1660373 3130019 | 14189 | -0.136 | -0.5674 | No | ||
| 41 | ERC1 | 1580170 2630717 6110762 6840280 | 14430 | -0.159 | -0.5780 | No | ||
| 42 | NOD2 | 2510050 | 14972 | -0.257 | -0.6033 | No | ||
| 43 | CXCL9 | 1570673 | 15063 | -0.281 | -0.6039 | No | ||
| 44 | RIPK2 | 5050072 6290632 | 15296 | -0.354 | -0.6112 | No | ||
| 45 | SOCS3 | 5550563 | 15517 | -0.438 | -0.6165 | No | ||
| 46 | IL18R1 | 270546 | 15526 | -0.442 | -0.6103 | No | ||
| 47 | IKBKG | 3450092 3840377 6590592 | 15750 | -0.544 | -0.6143 | No | ||
| 48 | TRAF6 | 4810292 6200132 | 16386 | -0.933 | -0.6346 | Yes | ||
| 49 | IKBKB | 6840072 | 16418 | -0.950 | -0.6221 | Yes | ||
| 50 | MPO | 2360176 2760440 5690176 | 16547 | -1.029 | -0.6136 | Yes | ||
| 51 | MAPK14 | 5290731 | 16662 | -1.120 | -0.6031 | Yes | ||
| 52 | TYK2 | 1660465 1740736 | 16700 | -1.152 | -0.5879 | Yes | ||
| 53 | NFKBIA | 1570152 | 17332 | -1.860 | -0.5942 | Yes | ||
| 54 | MAP3K14 | 5890435 | 17399 | -1.981 | -0.5682 | Yes | ||
| 55 | RELB | 1400048 | 17503 | -2.129 | -0.5421 | Yes | ||
| 56 | NFKB2 | 2320670 | 17622 | -2.349 | -0.5134 | Yes | ||
| 57 | RELA | 3830075 | 17641 | -2.379 | -0.4789 | Yes | ||
| 58 | LCK | 3360142 | 17786 | -2.667 | -0.4469 | Yes | ||
| 59 | BCL10 | 2360397 | 18080 | -3.458 | -0.4112 | Yes | ||
| 60 | STAT1 | 6510204 6590553 | 18110 | -3.562 | -0.3596 | Yes | ||
| 61 | STAT3 | 460040 3710341 | 18266 | -4.219 | -0.3051 | Yes | ||
| 62 | CD4 | 1090010 | 18290 | -4.362 | -0.2413 | Yes | ||
| 63 | CD3E | 3800056 | 18448 | -5.536 | -0.1673 | Yes | ||
| 64 | TNFRSF1A | 1090390 6520735 | 18474 | -5.755 | -0.0828 | Yes | ||
| 65 | TNFAIP3 | 2900142 | 18498 | -6.065 | 0.0064 | Yes |
